Using two-photon calcium imaging across more than 200,000 retinal ganglion cell axon boutons, this work shows that the mouse superior colliculus receives a near-complete sampling of retinal ganglion cell functional diversity. Functionally distinct response types are organized in systematic laminar gradients, including gradients of direction selectivity and contrast suppression properties.

Qiu, Y., Schmors, L., Zhou, N., Gonschorek, D., Akhmetali, M., Smith, C., Sumser, A., Vallens, M., Cadwell, C. R., Gabbiani, F., Joesch, M., Tolias, A., Berens, P., Euler, T., Sinz, F., Reimer, J., Franke, K. (2026). The functional organization of retinal input to the mouse superior colliculus. Current Biology.

* shared first authorship

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