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Nitric oxide modulates contrast suppression in a subset of mouse retinal ganglion cells

Gonschorek, D., Goldin, M. A., Oesterle, J., Schwerd-Kleine, T., Arlinghaus, R., Zhao, Z., Schubert, T., Marre, O., Euler, T.

eLife, 13, RP98742

First author

Summary

This work explores how nitric oxide functions as a neuromodulator affecting retinal ganglion cell activity. Using two-photon Ca²⁺ imaging and multi-electrode array (MEA) recordings, the study demonstrates that nitric oxide selectively modulates the suppression of temporal responses in a distinct subset of contrast-suppressed retinal ganglion cell types.

Citation

Gonschorek, D., Goldin, M. A., Oesterle, J., Schwerd-Kleine, T., Arlinghaus, R., Zhao, Z., Schubert, T., Marre, O., Euler, T. (2025). Nitric oxide modulates contrast suppression in a subset of mouse retinal ganglion cells. eLife, 13, RP98742. https://doi.org/10.7554/eLife.98742

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